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The boundaries between these disciplines and with other sciences, such as biochemistry, are not always clear-cut; and often, collaborative teams from various disciplines research together.
Most refrigerated vaccines are relatively stable at room temperature for limited periods of time, although certain vaccines are temperature-sensitive. Products stored in a closed refrigerator (or freezer, if appropriate) during a power outage may maintain their potency unless the power outage is of such duration that the refrigerator’s (or freezer’s) internal temperature rises significantly. It is recommended that thermometers be located in the refrigerator and freezer section so that temperatures can be read when power resumes to see if excursions outside of recommended temperatures have occurred. The „How Supplied/Storage and Handling“ section of the product label may also be consulted for information. Most vaccine manufacturers have filed data with CBER to support the stability of their products at somewhat elevated temperatures and related duration of storage; they may consult with CBER concerning the impact of temperature/time duration on product stability.
Yes. Generic medicines have to be �bioequivalent�. This means that they have to have the same active ingredient delivered to the body in the same way and have the same effect on the body as the original medicine. They don�t have to be manufactured using the same process.
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